The interpretation of the characteristics of alcoholic liver stages
Alcoholic liver disease, including fatty liver, alcoholic hepatitis, liver fibrosis, cirrhosis and hepatocellular carcinoma and so on. Alcoholics, about 2 / 3 can be developed for alcoholic liver disease. Of ethanol into the liver cells by the liver alcohol dehydrogenase, hydrogen peroxide decomposition and liver microsomal enzyme alcohol oxidase oxidation, the formation of acetaldehyde. Acetaldehyde on the liver cell has obvious side effects, so that there is resistance to metabolism, leading to degeneration and necrosis of liver cells.
Stage 1: mild alcoholic fatty liver generally do not have obvious symptoms, a small number of people, there may be fatigue, loss of appetite, abdominal distension, nausea, vomiting and other gastrointestinal symptoms, there will be fat, liver enlargement and other signs.
Stage 2: Once the alcoholic fatty liver developed to slow or alcoholic hepatitis-induced liver injury, the patient had prior to the onset heavy drinking is often short-term or long-term alcohol consumption, clinical symptoms of addition to the above, there may be fever, abdominal pain, diarrhea and so on, while others have significant weight loss, can occur in patients with elevated transaminases, serum bilirubin increased, anemia, and the performance increase in the number of neutrophils.
Stage 3: alcoholic cirrhosis in patients with early multiple no obvious symptoms may appear in the latter part of weight loss, loss of appetite, abdominal pain, fatigue, fever, dark urine, gum bleeding and other symptoms. Cirrhosis, there may be jaundice, ascites, edema, upper gastrointestinal bleeding and other symptoms, laboratory tests may have anemia, decreased white blood cells and platelets, serum albumin decreased globulin increased performance.