Patients with fatty liver in the end that what medicine?
Fatty liver is the crowd in today’s society as a frequently-occurring and common lifestyle diseases, the general population the incidence of fatty liver around 10%, obesity keep the crowd more than 50%, 50% of people with diabetes combined with fatty liver. Fatty liver is generally divided into three, one is a simple fatty liver, steatohepatitis 2 yes, 3 is a fatty cirrhosis of the liver. Many people believe that, hyperlipidemia and fatty liver is one thing. In fact, hyperlipidemia and fatty liver is completely two concepts, the two diseases. High blood lipids can lead to or facilitate the occurrence of fatty liver, and some patients with fatty liver lipid was not high.
Clinical findings, patients with fatty liver using a number of lipid-lowering drugs, fatty liver not only failed to reduce, but more emphasis on healing. This is because the cholesterol-lowering drugs does not reduce the deposition of fat in the liver’s sake. Then, accompanied by high blood cholesterol in patients with fatty liver can be lipid-lowering treated? Study confirmed that the fatty liver associated with high cholesterol can not be rashly applied lipid-lowering drugs. On the one hand, most of the cholesterol-lowering drugs are liver toxicity, can lead to intrahepatic cholestasis, causing jaundice or drug-induced liver damage and even lead to cirrhosis and liver failure; the other hand, cholesterol-lowering drugs have a “drive fat” role , can in the blood lipids, “driven” to the liver, while liver fat accumulation within the already existing, so a large number of difficult to deal with influx of lipids, fat will accumulate in the liver, so fatty liver disease worse. Most experts believe that the treatment of fatty liver in principle, to use lipid-lowering drugs, if the high blood lipid levels can be based on the comprehensive treatment and appropriate for lipid-lowering drugs, and close monitoring of liver function changes, if necessary, withdrawal. Treatment of fatty liver, the key is to remove the cause, such as alcoholic fatty liver disease have alcohol, non-alcoholic fatty liver disease will have to change their lifestyle deprivation Feigan, increasing physical activity, weight control.
Fatty liver treatment options are:
① to reduce liver fat deposition drugs: the first polyene phosphatidyl choline, trade name Essentiale, the main component necessary for the human body phospholipids, can maintain cell membrane stability and promote recovery of the biofilm, reducing inflammation, promoting liver cells transport cholesterol and triglycerides, reduce fatty infiltration of liver cells and improve lipid metabolism, is commonly used in clinical treatment of fatty liver drug; ursodeoxycholic acid can reduce the liver fat content, increasing bile lipid excretion, protecting the liver cell function.
② Anti-oxidants: Vitamin E, A, can inhibit lipid peroxidation involved in liver fat metabolism, reducing liver inflammation, contribute to the treatment of fatty liver; Reduced glutathione, there are anti-lipid peroxidation and protect liver cells The role that can nourish the liver, fat, antioxidant and anti-fibrosis effect of better treatment of fatty liver, the elevated transaminase steatohepatitis is more applicable; water fly hormone (Yiganling) is currently recognized as the anti-fatty liver is not the lack of drugs, can be against free radicals and lipid peroxidation, stimulate protein synthesis promoting liver cell injury rehabilitation, significant improvement in symptoms, so that to reduce aminotransferase, as well as certain anti-fibrosis.
③ improving insulin resistance drugs: a study found that patients with fatty liver in the blood insulin levels higher, but sensitivity decreased, meaning that insulin are numerous, but it does not work or effect is small, it will lead to increased blood sugar, leading to diabetes , is called “insulin resistance.” Blood insulin to lower blood sugar do not complete the work, but “proper job”, a large number of break down fats, so that free fatty acids increased, thereby promoting the formation of fatty liver, which is often associated with diabetes causes of fatty liver. Fatty liver disease exacerbated by insulin resistance, so that diabetes is more serious, forming a vicious cycle. Therefore, improving the “insulin resistance”, both treatment of diabetes, but also the treatment of fatty liver. Rosiglitazone maleate (Avandia) have this effect, treat insulin resistance. In addition, with two isopropylamine dichloroacetate treatment of non-alcoholic fatty liver disease, can reduce cholesterol and fatty acid synthesis, the promotion of glucose oxidation, reducing blood fat, lipid speed operation, so that to reduce fatty liver.
④ traditional Chinese medicine treatment: the choice of Alismataceae, red sage root, peach kernel, Cordyceps sinensis, habitat, health hawthorn, lotus leaf, bacteria Chen, Shouwu, paeonol and other prescriptions.