Lipid-lowering drugs on fatty liver is invalid
Fatty liver with hyperlipidemia who do not, without lipid-lowering treatment; and fatty liver with hyperlipidemia who should be the basis of the first treatment. With the ultrasonic examination in the examination of a large number of applications, found that the rate of fatty liver is increasing. That some patients, fatty liver since it is a kind of excessive lipid deposition in liver disease, then it should be taking lipid-lowering medication. This understanding correct? I encountered in clinical practice, two patients, it is representative.
34-year-old Mr. Zhang, non-drinking history, body mass index of 27. Two years ago, upper abdominal B-ultrasound of fatty liver was found, it has been taking lipid-lowering drugs, a recent review, no significant decline in body weight, B is still super-fatty liver, and abnormal liver function in the transaminase.
58-year-old Lee teacher, no drinking history, body mass index 32. A year ago, by B-ultrasonography and CT examination revealed fatty liver, while patients with hypertension, hyperlipidemia and diabetes, had abnormal liver function. Later, under the guidance of a doctor through diet control and physical activity, supplemented by liver protection therapy, weight loss within one year about 10%, liver function returned to normal, CT showed the liver fat deposition significantly better than before.
Why is the fatty liver but there are different endings then? To answer this question, must understand the following two points.
First of all, to understand how the body fat and blood lipids matter. We say that a person’s body organizations there a certain amount of adipose tissue, the liver is no exception, it is rich in fat tissue of the organ, but with normal levels within a certain range, more than this quantity can cause fatty liver. The lipid transport is a state of fat, fat in the intestine after digestion, absorption from the small intestine into the bloodstream, in the blood re-synthesis of triacylglycerol, cholesterol and a variety of lipoproteins, lipids are mobile and constantly updated, the normal circumstances to maintain homeostasis.
However, genetic or acquired factors, such as hobbies high-fat diet, less exercise and other unhealthy lifestyle can lead to hyperlipidemia. Hyperlipidemia is a long-term high blood pressure, coronary heart disease and other cardiovascular and cerebrovascular diseases and other metabolic syndrome risk factors, doctors often under the elevated level of blood lipids for lipid-lowering drugs, in the hope that by lowering blood lipids to reduce the above diseases.