Hepatitis C disease can not be delayed
The majority of chronic hepatitis C from acute hepatitis C evolved. For chronic hepatitis C antiviral therapy, the views of experts are basically the same; but for acute hepatitis C (HCV) anti-viral treatment, has also failed to reach a consensus. According to recent information we have at home and abroad to make the following observations, for reference.
Anti-virus as soon as possible
As you know, acute hepatitis B in general do not need anti-virus treatment, because it is obvious self-limiting disease, 2 months or so can be cured, self-clearance of hepatitis B virus, immune function, and produce protective antibodies – anti-HBs. So the need for anti-virus in acute hepatitis C treated? Practice has proved that the treatment should be given antiviral drugs as anti-viral treatment can effectively prevent the chronicity of acute hepatitis C. Chronic HCV infection incidence is relatively high, up to 50% ~ 85%. Reported in the literature, hepatitis B virus (HBV) infection to the development of liver cancer, the average time of 20 to 40 years, while the HCV progressed to liver cancer, the average time of 20 years or so, compared with HBV infection develop liver cancer, the average time is short . It also prompted anti-viral treatment urgency and necessity.
When given to antiviral drugs
Acute hepatitis C antiviral drug given to the timing of this day is still controversial. Abroad, the information from the current perspective, seems to tend to “wait and see” approach, that is, acute HCV infection have a certain spontaneous clearance rate, without any treatment measures, in the 2 to 3 months to 52% of the patients spontaneously body cleared HCV, and more reported that the spontaneous clearance rate of 73.3%. For this kind of patient is not taking medication, would not only relieve the pain and troubles of the medication, but also for the patients are saving money? If “such as” 2 ~ 3 months, the patient did not spontaneously cleared HCV, and then given to antiviral drugs and not too late, the efficacy and early treatment are the same, does not increase the incidence of chronic. However, this spontaneous clearance of HCV infection with the patient genotypes, age, sex, infection and other relevant channels. HCV genotype 1, age, high, male, infected through blood transfusion, etc., spontaneous clearance rate of the low. China’s hepatitis C patients with HCV infection in more than one type of gene, infection is also common in the elderly, so “wait and see” approach is not suitable for China’s actual situation.
In China, if a patient was diagnosed with acute hepatitis C, elevated aminotransferases, although minor symptoms, so that he “and” 2 ~ 3 months is very realistic. Therefore, once the diagnosis of acute hepatitis C was established, it is necessary and timely given antiviral treatment. Developed in China in 2004, “Hepatitis C Prevention Guide” also did not say “wait and see.” One is comparatively early drug use and “such as” these two approaches, the former high rate of virus clearance, chronic low.