Fatty liver drug therapy should be a festival of the system
Patients with fatty liver, some of the things no obvious symptoms except weight gain. Most patients have fatigue, loss of appetite, abdominal distention, diarrhea and other symptoms. Some because of liver volume increases, the liver capsule was pulled and the sense of liver pain. Patients with a history of hepatitis, often consider themselves heavier and more restrictions on the activities of liver disease, increase nutrition, this may instead cause weight gain, fatty liver aggravated liver pain increased, forming a vicious cycle. The small bile duct due to compression of individual patients may have mild jaundice, there is only a part of the performance of long-term patients with mild to moderate elevated aminotransferases, without any discomfort only in the physical examination found elevated aminotransferases, blood lipids, especially three acyl Gan oil increased.
Many drug treatment of fatty liver, mainly divided into lipid-lowering drugs, protecting liver fat drugs and Chinese medicine. But the need to note is that the current treatment of fatty liver is still wipe out the cause, the positive treatment of the primary disease and adhere to a reasonable diet-based drug treatment only play a supporting role, should be based on fatty liver disease etiology and rational choice.
Fatty Liver Treatment Points
1. Alcoholics: for simple fatty liver and in alcoholic fatty liver-based toxic liver disease, alcohol, the usual 2 to 4 weeks liver function return to normal.
2. Diet: eat low-fat, high protein, low sugar, low calorie, and fiber-rich foods and get enough vitamin B1, B2, B6, and folic acid, zinc, choline, methionine.
3. Exercise training: increased physical activity, weight control.
Drug adjuvant therapy
1. Non-prescription drugs:
Myo-inositol can promote the metabolism of fat in the liver, a sub-0.5g ~ 1g, 1 3 times a day; Tiopronin (Tiopronin) can improve liver cell function, preventing triglyceride accumulation, one sub-0.lg ~ 0.2 g, 1 3 times a day for 12 weeks; compound dichloro-diethyl isopropylamine acetate tablets (Lee liver can be) as the active component of vitamin B15 can reduce fat deposition, promoting regeneration and 1 1 ~ 3 films, 1, three times; D-glucuronolactone can enhance liver detoxification function, reduce fat accumulation; to γ-GT a higher option of glutathione intramuscular injection, a sub-50mg ~ 100mg, 1 1 times.
2. Traditional Chinese Medicine:
Oral Bupleurum Shuganwan, 1 a pill, 1, 2 times, can be Shugan Qi, reduces swelling, pain, for no Shu qi, liver qi stagnation, Xiong Xie ruffian nausea, Shi Zhi unclear, vomit folic acid water embolism treatment, if there mamillata little moss, Kouzao throat, upset insomnia Yin deficiency should be promptly discontinued; persistent hepatitis can choose Wujibaifeng Pills and 1 a pill, 1, 2; two threatening puffiness, loss of appetite, playing every other vomiting, stomach pain, hospital, could take Shugan and stomach pills, Miwan 1 2 pill, small Honey pill 1 9g, 1 to 2 times; two threatening puffiness, chest bored, vomiting, nausea, gas will not ring true against the person, optional transfer service Shugan Qi Wan, 1 6g, 1 1 times 2 times. In addition, many Chinese herbal medicines have a role in lipid-lowering, such as fleece-flower root, red sage root, Alisma Rhizoma, cassia seed, hawthorn and so on.
Adjuvant treatment of fatty liver common adverse drug reactions
Oral Tiopronin occasionally fever, rash, stomach discomfort, nausea, vomiting, abdominal pain, diarrhea, abnormal taste reaction; unusual fatigue, numbness and other reaction; long-term high doses, there may be proteinuria or nephrotic syndrome , it should be noted that
After taking Inosine occasionally stomach discomfort, mild diarrhea, abdominal pain and other symptoms.
Prescription drugs should be used under the guidance of a doctor, adverse drug reactions as detailed instructions, not repeat it here.
Fatty liver evaluation of the role of adjuvant therapy drugs
At present, the treatment of fatty liver despite as many as 100 kinds of drugs, but only a weak role of adjuvant therapy is required long-term use. To obtain better clinical results, we must eliminate the cause, including alcohol, reduce high-fat intake, medication and so on as little as possible. At the same time it should be added vitamins (vitamin B, vitamin B complex tablets, vitamin E-C mixture, Victoria propylamine), and minerals and trace elements (such as iron, zinc, calcium). “National Non-prescription drug directory” included adjuvant treatment of fatty liver drug-glucuronolactone, inosine, dichloro-ester acid isopropylamine, inositol and so on.
1. D-glucuronolactone: You can enhance liver detoxification function. D-glucuronolactone into the human body, under the action of the enzyme into glucuronic acid, and the body through the base or carboxyl containing poison, forming non-toxic or low toxic glucuronide conjugates and excreted from the urine . Apply to acute and chronic hepatitis and fatty liver, cirrhosis of the liver of adjuvant therapy. Oral, adult 1 100mg ~ 200mg, 1 port 3 times; children under 5 years of age, a time 50rng; 5 years old children, a sub-100mg, 1 3 times a day.
2. Inosine: Liver enzymes drug. Muscle in the body back into acid and adenosine triphosphate, the energy involved in cell metabolism and protein synthesis. Can improve coenzyme A with pyruvate oxidase activity, so that cells in the hypoxic condition continued metabolism, activation of liver function and promote recovery of damaged liver.
3. Dichloro diethyl ester isopropylamine: can improve liver function, reduce liver fat deposition, promote regeneration of liver cells injury, for the adjuvant treatment of early fatty liver and cirrhosis, 1 40mg, 1 3 times a day.
4. Myo-inositol: the promotion of liver fat metabolism, reduce blood lipids for prevention and treatment of fatty liver. Adult oral 1 0.5g ~ lg, l 3 times a day.
Fatty liver in the course of treatment, should reduce the liver toxic drugs. A variety of drugs into the human body by the liver metabolism and detoxification, excessive medication and thus increase the burden of the liver first, second, some drugs with liver toxicity, may damage liver cells. Therefore, to carefully select drugs, less clothes, or try to agree with unnecessary drugs.