Fatigue is the standard signs of cirrhosis of the liver
Cirrhosis of the liver is a common chronic liver disease is determined by one or more causes of long-term or repeated effect, causing diffuse damage to the liver. Early clinical liver function due to a strong compensation may be no obvious symptoms; the latter part of the multiple systems involved, to liver dysfunction and portal hypertension as the main performance, and often appear gastrointestinal hemorrhage, hepatic encephalopathy, secondary infection , cancer and other serious complications.
Published in the May Journal of Gastroenterology, No. A study shows that fatigue is the primary biliary cirrhosis (PBC) in patients with symptoms of the most remarkable specificity.
Newcastle University, Liver Research Center, Dr. Jennifer Goldblatt noted that previous studies typically use subjective or non-quantitative fatigue assessment tools, therefore, it is not clear the actual extent of fatigue in patients with PBC.
Researchers chose a certain geographical patients, age and gender-matched normal controls and chronic liver disease control patients, the use of objective methods of measurement of fatigue impact score (FIS), to assess primary biliary cirrhosis (PBC) in patients with fatigue .
It was found that patients with an average of FIS was significantly higher than community controls (40 to 28) and chronic liver disease controls (21). In addition, 11 cases of liver transplantation (on average after 3.5 years) rate of fatigue in patients with advanced disease, patients with non-identical transplant.
Dr. Goldblatt that PBC patients with fatigue is a significant and specific performance. However, the symptoms are not common, the affected patients is less than the previous forecast.
The cause of cirrhosis of the liver are many that several factors can cause cirrhosis of the liver.
1. Viral hepatitis viral hepatitis in China (especially hepatitis B and C) are the main cause cirrhosis, most of which developed into a portal cirrhosis. Cirrhosis in patients with HBsAg-positive liver cells often significant, the positive rate of 76.7%.
2. Chronic alcoholism in the United States and Europe due to alcoholic liver disease caused by cirrhosis of the liver can account for about 60% to 70%.
3. Nutritional deficiencies, animal experiments showed that a lack of choline or methionine feeding food animals, through the development of fatty liver cirrhosis.
4. Poison poisoning of certain chemical poisons such as arsenic, carbon tetrachloride, yellow phosphorus and other long-term effect on the liver can cause cirrhosis of the liver.