An omni-prevention and treatment of fatty liver
Clinically, fatty liver can be a separate disease, but also can be a systemic disease occurs in the liver of a pathological changes. According to statistics, in the general population about 10% of the people there are varying degrees of hepatic steatosis. So, can cause liver steatosis What causes it?
1, nutritional imbalance
1. Hunger: chronically hungry people tend to hypoglycemia, low blood sugar may stimulate the person’s sympathetic to accelerate the decomposition of the body fat. Once an excessive amount of fatty acids into the patient’s blood, so that it will be an increase in free fatty acid in the blood caused by the accumulation of liver fat. However, with the extension of the time people are fasting, the body’s fat metabolism of other organizations will be generated by the heat as the body needs a major source of heat, which allows the liver fat accumulation was slightly reduced.
2. High-fat diet: long-term intake of high fat diets may be a result of the blood in chylomicrons and non-esterified fatty acids caused an increase in fatty liver. Most high-fat diet-induced fatty liver patients often accompanied by a lack of protein, while protein and fat may aggravate the imbalance between fatty infiltration of liver cells.
3. Low-protein diet: lack of protein intake leading to fatty liver is another important reason. Clinically, long-term inadequate intake of protein malnutrition known as “malignant malnutrition.” This is because the patient has been using starch-based foods, and their carcasses will be the lack of protein. Then the body’s synthesis of albumin will be a corresponding reduction in their plasma triglycerides and very low density lipoprotein levels will decline, which allows it to accelerate the decomposition of adipose tissue, leading to an increase in free fatty acid in the blood : On the other hand due to the body in patients with impaired apolipoprotein synthesis, so that triglycerides are released into the blood slowed down, which can cause massive accumulation of fat in the liver caused by fatty liver.
Second, alcohol consumption
Accumulation of fat in the liver of a person the amount of alcohol consumption and drinking with the duration of a clear relationship. Alcoholic fatty liver in patients with accumulation of fat in the liver to triglyceride-based, if the accumulation of excess fat can make the weight of the liver to reach 2-2.5 kg, and some even up to 4 ~ 5 kg.
Third, obesity
Associated with significant obesity patients with multiple liver fatty infiltration and different degrees of fatty liver. Lead to fatty infiltration of the liver in patients with the reasons for an increase in their body fat and blood levels of free fatty acids related to the rise. In addition, if the nutritional supplements in patients with hepatitis recovery excess or less active, can also lead to fatty liver after hepatitis.
4, diabetes mellitus
Clinical studies confirm that about 37% ~ 46% of diabetes patients are complicated with fatty liver, while nearly half of patients with fatty liver are combined with diabetes. Insulin-dependent diabetes because of their low levels of insulin, glycogen reserves inadequate, it is often through the decomposition of fat to provide energy for the body, but once you can break up fat cells in patients with excessive blood levels of free fatty acids increased, thereby can lead to severe fatty infiltration of the liver; non-insulin-dependent diabetic patients as compared with the body shape are mostly obese, the reasons for its occurrence of fatty liver is an increase in the fatty tissues of their body and their blood levels of free fatty acids related to the rise.
5, pregnancy
Acute fatty liver of pregnancy more common in young pregnant women in the first of its onset is usually late in their pregnancy (36 to 40 weeks). Although the disease is relatively rare in clinical practice, but once the disease is often serious condition in patients (similar to acute fulminant hepatitis), and the prognosis is poor, its case fatality rate as high as 80%. At present, leading to the mechanism of acute fatty liver of pregnancy is not yet clear, but some scholars believe that the incidence of acute fatty liver of pregnancy may be due to patients in late pregnancy, the body of catecholamine, renin and angiotensin Ⅱ level both increased, leading to liver metabolism of blood there was a serious obstacle. In addition, contraction of blood vessels many of the above active substances will accelerate the decomposition of fat of pregnant women, resulting in blood levels of free fatty acids increased rapidly, which can cause extensive fatty infiltration of liver cells.
6, drug poisoning
Certain drugs containing organic compounds or inorganic compounds, such as carbon tetrachloride, chloroform, yellow phosphorus, galactosamine, actinomycin D, flies, meat and vegetables people can occur such as fatty liver. They lead to the mechanism of fatty liver varies.
So how to proceed with fatty liver treated?
At present, the clinical treatment of fatty liver on the removal of its cause is still dominated. The one hand, patients with fatty liver should be noted that to adjust your diet, while appropriate choice of lipid-lowering drugs for symptomatic treatment in order to effectively control the further development of fatty liver disease or to be reversed.
One to carry out dietary conditioning
To adjust your diet is an important means for the treatment of fatty liver. People should be more normal intake of fresh vegetables, lean meat (as beef, mutton-based), and rich in lipophilic substances (choline, methionine) and food to lose weight. But be noted that patients with fatty liver usually still have the right amount of fat intake, and pay attention to controlling carbohydrate intake. This is because, when people intake of fat-free foods, its body can use sugars and amino acid synthesis of fatty acids, the precursor material, while the intake of too much sugar can also promote the secretion of insulin, so sugar into fat . So, different types of fatty liver patients how they should be eating it conditioning?
1. Obese patients with fatty liver: type of fatty liver in ensuring the normal intake of nutrients, under the premise should be appropriately reduced fat, carbohydrate and total calorie intake, eating vegetable oils to be elected and to limit intake of high cholesterol food income. Patients with this disease if we persist with this practice for one year can often reduce the 10 to 20 kg of body weight, while their liver fat deposition will follow subside. However, patients with fatty liver in the control diet must be appropriate, because it unduly restricted diet can lead to steatohepatitis and liver fibrosis, and enable patients electrolyte imbalance, hyperuricemia and ketosis and other adverse consequences.
2. Alcoholic fatty liver disease: simple-alcoholic fatty liver disease should be strictly abstinence, while we still need more intake of high-protein, high-calorie, high-vitamin diet to correct the malnutrition. Disease in patients with daily calorie intake of fat should not exceed 15% of total calories to 20%, and should be appropriate to reduce the intake of unsaturated fatty acids as unsaturated fatty acids can induce lipid peroxidation and increases liver tissue damage.
3. Malnourished patients with fatty liver: type of fatty liver common in nutrient intake or inadequate digestion and absorption in problems of chronic wasting disease, as well as people. To treat the disease, when patients should be based on high-protein, high-calorie, high vitamin and low-fiber diet mainly serious condition may increase with the complex amino acid preparations.
4. Diabetic patients with fatty liver: diet therapy in the treatment of diabetes plays an important role. Diabetic patients with fatty liver should be based on low-calorie, low-fat, high fiber diet consisting mainly of their intake of sugars contained in the heat of the total calories should be around 60%. Complicated with diabetic nephropathy in patients with fatty liver daily protein intake should be limited to 1 g / kg (body weight) or less in order to alleviate the burden on the kidneys.
5. Hyperlipidemic fatty liver patients: These patients with fatty liver can be obtained through the implementation of diet therapy cured. Treatment of the disease when the patient should be based on low-sugar, low fat, low cholesterol and high-fiber diet mainly to try to eat mushrooms, edible fungus, celery, and hawthorn and other food, in order to achieve blood cholesterol and reduce the liver fat deposition purposes.
6. In patients with fatty liver after hepatitis: type of fatty liver disease more common in patients recovering from acute hepatitis and chronic hepatitis, its causes are mostly due to excessive caloric intake in patients with lower level of activity caused by their weight increasing caused by accumulation of fat in their liver. The patients should be appropriately reduced fat, carbohydrate and total calorie intake, while also strengthening the physical exercise.
Second, for drug treatment
Pairs of fatty liver in drug treatment, including lipid-lowering therapy, Hugan Quzhi treatment and traditional Chinese medicine treatment.
1. Lipid-Lowering Treatment: Since the fatty liver and hyperlipidemia in close, so a long time, people have been using lipid-lowering drugs for the treatment of fatty liver, and have achieved a certain effect. At present the clinical lipid-lowering drugs commonly used are: choline, methionine, nicotinic acid and its derivatives, inositol, cholestyramine, clofibrate (clofibrate), bezafibrate (required lipid-lowering), elastase , the United States and other lipid-lowering. In addition, a number of new drugs, such as ciprofibrate, fenofibrate (Pluto fat fen), gemfibrozil, ASIMO Division (Le fat level), Kelibeite, benzyl chloride Bate, according to Tauber Special (benefit greasy), lovastatin, simvastatin and so on. These drugs all have lower serum triglycerides, cholesterol, low-density lipoprotein, and elevated the role of high-density lipoprotein, and thus of fatty liver also have a good effect. However, a wide variety of lipid-lowering drugs, most of effectiveness has not been very precise. Some of the larger lipid-lowering drugs have side effects, patients can, if incorrectly applied to increase its intrahepatic fat accumulation, or even cause or aggravate his liver insufficiency. Therefore, patients with fatty liver must be applied under the guidance of a doctor lipid-lowering drugs, and treatment should focus on to control diet, lower body weight-based.
2. Hugan Quzhi treatment: In recent years, some protect the liver cells and liver cells to correct the role of fat metabolism of drugs under active development among some of these drugs have begun clinical applications, such as: prostaglandin E (PGE ), the liver was Jian, Malotilate, taurine, glycine and other thiol-propionyl. Patients with fatty liver may wish to try these new drugs.
3. Chinese medicine treatment: A lot of traditional Chinese medicine such as Salvia, Chuanxiong, cassia seed, hawthorn, and other pairs of fatty liver Alisma have some efficacy in patients with this disease may be appropriate under the guidance of a doctor to apply these traditional Chinese medicine treatment in order to mitigate its symptoms. For example, the liver Qi stagnation can be used in patients with fatty liver Chaihushugan Powder (plus or minus) for treatment; Qi and Blood Stagnation-type can be used in patients with fatty liver Xuefuzhuyu Tang (plus or minus) for the treatment i phlegm resistance-type fatty Patients can be combined liver Sini San Dao Tan Tang (Modified) for treatment. In addition, some of the folklore of prescription, such as Quzhi drink (hawthorn, Alismataceae, Bupleurum), Ning lipid films (Atractylodes, Citrus, Pinellia, Salvia), platinum pill (alum, turmeric, etc.), as well as on the market for sale weight-loss drugs also have a certain lipid-lowering effect in patients with fatty liver may be selected as appropriate under the guidance of a doctor.