Alcoholic liver injury, female hazard even worse
My nearly 7 years, due to a large number of long-term drinking of potent liquor caused increased 28.5-fold in patients with alcoholism, the death toll increased by 30.6-fold. We all know that moderate alcohol consumption for most people’s health and there is no damage, a small amount of drinking some wine, such as wine, the body has certain advantages. However, long-term excessive drinking, especially in a high number of drinking wine, it will cause fatty degeneration of liver cells, inflammation, necrosis and fibrosis, eventually leading to cirrhosis or liver cancer. Edition invited to Beijing Tiantan Hospital, Gastroenterology, director of Dr. Xu Youqing give readers some things to talk about drinking and alcohol-induced liver disease prevention and treatment.
After the sick note
50-year-old Wang, a drinking history of 20 years, two years ago, diagnosed with alcoholic cirrhosis. During the Spring Festival because of continued high alcohol consumption are more entertaining, ascites, slurred speech, unsteady gait, aggressiveness and other symptoms. After hospitalization for sedation, hepatoprotective, diuretic and a series of symptomatic treatment, his condition has improved but he was clearly increased the extent of liver damage.
Xu Qing, director of presentations, such as the above-mentioned Mr. Wang as the patient, should first wine to quit, only the alcohol in order to prevent the further development of the disease; pay attention to proper rest; in liver protection under the guidance of a doctor, symptomatic treatment and nutritional support. In the diet, eating high-protein, high-sugar, low fat, low salt diet, such as an appropriate complement of plant protein, soy products, lean meat type (chicken, beef and mutton), milk type, rice, flour and other cereals, and Note added vitamin B, C, K and folic acid type more foods such as fresh fruit and vegetables.
In addition, Mr. Wang’s no need to fear, we should insist on one to two months on a regular basis to the hospital for review, if there is abdominal distention, decreased urine output, lower extremity edema and other symptoms should go to hospital.
Understanding of alcoholic liver disease
Xu Qing, director of introduction, alcoholic liver disease is due to the long-term excessive drinking, resulting in deposition of fat in liver cells, degeneration, necrosis and regeneration, ultimately leading to liver fibrosis and cirrhosis, and may even cause the occurrence of liver cancer. Mainly include alcoholic hepatitis, alcoholic fatty liver and alcoholic cirrhosis.
I want to clarify that not all drinkers can lead to alcoholic liver disease. The occurrence of alcoholic liver disease and alcohol dose, the patient’s nutritional status, genetic and metabolic characteristics of the. The development of alcoholic liver disease and alcohol abuse is closely related to dosage and length of time. Although not all alcoholics have undergone significant liver damage, but long-term drinking can easily damage the liver occurs, women of the dangers of alcohol more. China Liver learn to alcoholic liver disease in the diagnostic criteria for alcoholic liver disease is defined as: general drinking more than five years, equivalent to the amount of ethanol as follows: males more than 40 grams per day; females is greater than 20 grams per day ; or 2 weeks, a large number of drinking history (more than 80 grams per day) due to abnormal liver function, and the emergence of related clinical symptoms. Ethanol conversion formula is: g = alcohol consumption (ml) × alcohol content (degrees) × 0.8 (the proportion of ethanol).
Clinical manifestations of disease
Xu Qing, director, said, alcohol-induced liver disease is a chronic injury process, and recently there’s no obvious clinical symptoms. Alcoholic liver disease in the course of the occurrence and development of alcoholic fatty liver, alcoholic hepatitis and alcoholic liver cirrhosis at different stages of liver damage.
Alcoholic fatty liver generally do not have symptoms, some may appear weak, fatigue, loss of appetite, abdominal distension, nausea, vomiting and other performance, there will be fat, liver enlargement and other signs.
Alcoholic hepatitis is often caused due to short-term high alcohol consumption, clinical manifestations in addition to symptoms of nonalcoholic fatty liver, there are fever, yellow urine, weakness, abdominal pain, diarrhea, and there is significant weight loss. Laboratory examination can be expressed as mean corpuscular volume increased, elevated aminotransferases, GGT increased, serum bilirubin increased and so on.
Early in patients with alcoholic liver cirrhosis can also be asymptomatic, may appear in the latter part of weight loss, loss of appetite, abdominal pain, fatigue, fever, dark urine, gum bleeding and other symptoms. Cirrhosis, there may be jaundice, ascites, lower extremity edema, upper gastrointestinal bleeding and other symptoms.
Alcoholic liver disease was mainly due to the long-term liver damage caused by alcohol is not contagious, family members, friends and colleagues do not have to worry about being infected.
Alcoholism can cause illness
Director Xu said, alcoholism and alcoholic liver disease have a close relationship. Short-term or one-time heavy drinking can cause acute alcoholism. The long-term heavy drinking (a few months or years) the most common injury sites were liver,
Excessive drinking or taking too much alcohol can cause central nervous excitement or inhibition state, called acute alcoholism. Clinical exciting period can be divided into three namely, ataxia period, coma period. Mild as the excitement phase, showed to speak in full flight, emotionally unstable, easily swayed by emotions, facial flushing or paleness, conjunctival hyperemia, may have abdominal discomfort, nausea and even vomiting. For the period of moderate ataxia appeared uncoordinated muscle movement, speech vague, blurred vision, diplopia, gait instability. Severe as the sleeping period, the performance of the state of lethargy, vomiting, slow breathing, heart rate, particularly in severe incontinence, convulsions, coma, respiratory paralysis and death may occur.
The most effective preventive measure is abstinence
Xu Qing, director of presentations, alcoholic liver disease the most effective preventive measure is to stop drinking or control alcohol consumption, as consumption of low alcohol or non-alcoholic drinks. Can not be too much reliance on the current preventive health care products on the market, as many brands of health products, therapeutic mechanism is unclear, difficult to determine efficacy.